Creighton went head-to-head with DePaul on Tuesday night. The Jays were off to a good start with the first points on the board, courtesy of Steven Ashworth. Jamiya Neal accounted half of Creighton's points as they led 16-7. A few minutes later, Neal was in double digits for the first half.

Led by Neal Jamiya's 14 points, the Creighton Bluejays defeated the DePaul Blue Demons 73-49. The Bluejays improved to 13-6 with the win and the Blue Demons fell to 10-10.