Cushing syndrome, which is also called Cushing’s syndrome, is a disorder that happens when your body makes too much of the stress hormone cortisol over a long period of time, according to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

On the January 22 episode of Call Her Daddy podcast, Amy Schumer sat down with host Alex Cooper and shared that online trolls triggered her Cushing Syndrome diagnosis.

Internet trolls partly aided doctors in diagnosing Amy Schumer with Cushing syndrome, but patients can go years without a diagnosis. Schumer opened up about her February 2024 diagnosis on the “Call Her Daddy” podcast Wednesday,

I don't know if Amy Schumer knew what Cushing syndrome was back in 2024, but she definitely didn't know she had it until literal doctors on the internet started commenting on her face. Speaking to Alex Cooper on Call Her Daddy,

Amy Schumer was diagnosed with Cushing syndrome, a hormonal disorder caused by high levels of cortisol in the body — thanks to comments from people on the internet who noticed her "puffier face," she recently shared.

Amy Schumer, 43, is crediting online trolls with her rare Cushing syndrome diagnosis. On a January 22 episode of the Call Her Daddy podcast, the actress shared that she first ignored comments about her "puffier than normal" face.