It's Buffalo Bills vs New England Patriots in Week 16 of the NFL season. Can Josh Allen and James Cook keep it rolling ...

James Cook scored two touchdowns, Buffalo’s defense forced three second-half turnovers and the AFC East champion Bills ...

The Patriots have been tabbed as 14-point underdogs by several oddsmakers against the Bills. The post Patriots vs. Bills live ...

The New England Patriots (3-11) and the Buffalo Bills (11-3) meet Sunday in a Week 16 game at Highmark Stadium. Kickoff is ...

The Buffalo Bills won a nail-biter against the New England Patriots, 24-21, in Week 16 action. The Bills, a massive ...

New England Patriots quarterback Drake Maye (10) throws while pressured by Buffalo Bills linebacker Von Miller (40)cduring the first half of an NFL football game in Orchard Park, N.Y., Sunday, Dec. 22 ...

James Cook will lead the Buffalo Bills into their game versus the New England Patriots at Highmark Stadium on Sunday at 4:25 ...

The Bills gave up 521 yards playing without starting safeties Taylor Rapp (neck/shoulder) and Damar Hamlin (ribs), and ...

The Buffalo Bills (11-3) are home at Highmark Stadium to take on division rival New England Patriots (3-11) at 4:25 p.m.

The Bills host the Patriots Sunday afternoon at Highmark Stadium. Here is Sal Maiorana's in-depth preview of the game.

The Bills enter the game as a two-touchdown favorite and have the second-highest point spread in the NFL this week.

NFL Week 16 odds, picks, predictions, TV channel, streaming information for Sunday football game between New England Patriots ...